Symyx Technologies Launches Content Web Service

Symyx Technologies, Inc. (Nasdaq:SMMX) is pleased to announce that researchers using Symyx Available Chemicals Directory® (previously MDL Available Chemicals Directory or MDL ACD), the largest structure-searchable collection of commercially available chemicals in the world, now have the option of accessing up-to-date ACD data via the Internet using a dedicated XML-based Web Service. The Symyx ACD Web Service was developed with design input from a global pharmaceutical R&D organization seeking business process efficiencies and a simplified mechanism for distributing dynamically updated chemical sourcing data to globally dispersed project teams. "The ACD Web Service from Symyx accelerates R&D by dynamically injecting real-time chemical sourcing data into the R&D process,” said Timothy Campbell, President of Symyx Software. "Using this new Web Service, research organizations can update internal data sources and deliver sourcing data directly to scientists using in-house-developed applications that integrate with existing laboratory workflows.” Used by more scientists than any other supplier database worldwide, Symyx ACD contains more than 605,000 structures representing approximately 1.7 million products and 3.4 million packages available for purchase, in bulk and research quantities. The database can be searched by structure and substance identifiers to retrieve all available data. The ACD Web Service is part of a growing new generation of Symyx workflow tools available to researchers today. For more information about the Symyx ACD Web Service and other workflow and content solutions, visit www.mdl.com. About Symyx Symyx Technologies, Inc. is the R&D execution partner to the life sciences, chemicals, energy, consumer products and electronics industries. Symyx provides electronic lab notebook and scientific decision-support software, automated lab systems (workflows) and collaborative research services to improve R&D productivity. In October 2007, Symyx acquired MDL Information Systems, Inc., a leading provider of innovative informatics software, databases and services that accelerate successful scientific R&D by improving the speed and quality of scientists’ decision making. Information about Symyx, including reports and other information filed by Symyx with the Securities and Exchange Commission, is available at www.symyx.com. Available Chemicals Directory is a registered trademark of Symyx Technologies, Inc. All rights reserved. All other trademarks mentioned in this document are the property of their respective owners.