Press release: Curetis’ Subsidiary Ares Genetics Introduces NGS Services for Pharma and Public Health Sector at Upcoming ECCMID 2019

• Strain-typing and AMR detection of clinical isolates based on ARESdb
• Set-up of own NGS service laboratory in Vienna, Austria

Vienna, Austria, Holzgerlingen, Germany, and Amsterdam, The Netherlands,
April 12, 2019, 08:00 CET – Ares Genetics GmbH (Ares Genetics), a Curetis Group Company (Curetis N.V.; EURONEXT: CURE), today announced the introduction of new service offerings in molecular microbiology at the upcoming 29th European Congress of Clinical Microbiology & Infectious Diseases (ECCMID), which will take place in Amsterdam, the Netherlands, on April 13-16, 2019.

From mid-2019, Ares Genetics will offer its ARESupa Universal Pathogenome Assay for whole-genome sequencing of bacterial strains isolated from clinical specimens. Applications will be in epidemiology, infection control, and outbreak analysis for customers in the public health sector and the pharmaceutical industry. Based on the genetic profile of the respective clinical isolate, ARESupa precisely identifies the bacterial strain and detects antimicrobial resistance (AMR). Ares Genetics expects that ARESupa will greatly facilitate the monitoring of AMR evolution and spreading at the molecular level and provide rapid insights into origin and dynamics of outbreaks of critical, often multi-drug resistant pathogens in hospitals and care facilities.

ARESupa combines next-generation sequencing (NGS) with data analysis and interpretation powered by ARESdb, Ares Genetics’ AI-powered reference database on the genetics of antimicrobial resistance. ARESdb currently covers detailed whole-genome sequencing data of more than 35,000 bacterial strains, including quantitative data on the resistance phenotype for more than 100 antibiotics.

ARESupa will be offered out of Ares Genetics’ NGS service laboratory currently being set up in Vienna, Austria. The NGS service laboratory will be headed by Dr. Johannes Weinberger, who recently joined Ares Genetics from the Austrian Red Cross where he set up an NGS facility for the Department of Histocompatibility and Immunogenetics. He brings about ten years of experience with NGS technologies in the public sector as well as the healthcare industry.

While ARESupa initially is offered for non-diagnostic uses in the public health sector and the pharmaceutical industry, the Company is also working on an ARESupa laboratory-developed test (LDT) for the detection of pathogens and AMR in severe hospital-acquired infections that will initially be launched for selected high-need indications that are difficult to diagnose with conventional methods.

"Already today, there is wide-spread acceptance of the benefits of NGS for AMR surveillance, pathogen epidemiology, the tracking of outbreaks as well as for antimicrobial drug development,” explained Dr. Andreas Posch, Managing Director and CEO of Ares Genetics. "Hence, launching our Universal Pathogenome Assay NGS services for isolate identification, typing and quantitative genetic AMR profiling is an important milestone in the execution of our business plan that ultimately aims at providing universal NGS-based infectious disease diagnostics,” Dr. Posch added.

"We expect that our new NGS service laboratory will greatly accelerate our projects with pharmaceutical companies such as Sandoz as well as collaborations with diagnostics industry players,” said Dr. Achim Plum, Chief Business Officer of the Curetis Group and Managing Director of Ares Genetics. "The ability to perform NGS in our own laboratory comes timely as we are in discussions with numerous companies on further projects using our expanded service offerings.” 

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Ares Genetics at ECCMID 2019

For more information on ARESupa and Ares Genetics licensing and service offerings for the diagnostics and pharmaceutical industries visit Ares Genetics at the Curetis Group Booth
(Booth #1.65) at ECCMID 2019 in Amsterdam, Netherlands, on April 13-16, 2019.   

About Curetis and Ares Genetics

Curetis N.V.’s (Euronext: CURE) goal is to become a leading provider of innovative solutions for molecular microbiology diagnostics designed to address the global challenge of detecting severe infectious diseases and identifying antibiotic resistances in hospitalized patients.

Curetis’ Unyvero System is a versatile, fast and highly automated molecular diagnostic platform for easy-to-use, cartridge-based solutions for the comprehensive and rapid detection of pathogens and antimicrobial resistance markers in a range of severe infectious disease indications. Results are available within hours, a process that can take days or even weeks if performed with standard diagnostic procedures, thereby facilitating improved patient outcomes, stringent antibiotic stewardship and health-economic benefits. Unyvero in vitro diagnostic (IVD) products are marketed in Europe, the Middle East, Asia, and the U.S.

Curetis’ wholly owned subsidiary Ares Genetics GmbH offers next-generation solutions for infectious disease diagnostics and therapeutics. The ARES Technology Platform combines the presumably most comprehensive database worldwide on the genetics of antimicrobial resistances, ARESdb, with advanced bioinformatics and artificial intelligence tools.

For further information, please visit www.curetis.com and www.ares-genetics.com.

Legal Disclaimer

This document constitutes neither an offer to buy nor an offer to subscribe for securities and neither this document nor any part of it should form the basis of any investment decision in Curetis.

The information contained in this press release has been carefully prepared. However, Curetis bears and assumes no liability of whatever kind for the correctness and completeness of the information provided herein. Curetis does not assume an obligation of whatever kind to update or correct information contained in this press release whether as a result of new information, future events or for other reasons.

This press release includes statements that are, or may be deemed to be, "forward-looking statements.” These forward-looking statements can be identified by the use of forward-looking terminology, including the terms "believes,” "estimates,” "anticipates,” "expects,” "intends,” "targets,” "may,” "will,” or "should” and include statements Curetis makes concerning the intended results of its strategy. By their nature, forward-looking statements involve risks and uncertainties and readers are cautioned that any such forward-looking statements are not guarantees of future performance. Curetis’ actual results may differ materially from those predicted by the forward-looking statements. Curetis undertakes no obligation to publicly update or revise forward-looking statements, except as may be required by law.

Contact details

Curetis
Max-Eyth-Str. 42
71088 Holzgerlingen, Germany
Tel. +49 7031 49195-10
pr@curetis.com or ir@curetis.com
www.curetis.com - www.unyvero.com

International Media & Investor Inquiries
akampion
Dr. Ludger Wess / Ines-Regina Buth
Managing Partners
info@akampion.com
Tel. +49 40 88 16 59 64
Tel. +49 30 23 63 27 68

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• 20190412_PR_AresGenetics_ECCMID_final_approved