Isonics to Provide Live Demonstrations of Homeland Security Products at ISC West Conference in Las Vegas; Company to Exhibit Products at Leading Security Industry Trade Show

Isonics will feature several advanced technology homeland securityproducts and services designed to address large segments of the globalsecurity industry marketplace, including chemical threat and explosivedetection systems based on its proprietary ion mobility spectroscopy(IMS) technology, and its recently announced intelligent videosecurity surveillance solutions.

Among product lines Isonics will exhibit and demonstrate at theISC West conference are:

-- The EnviroSecure(TM) IMS-based "sniffer" systems that monitor air quality in buildings and other public venues for the presence of airborne chemical threats;

-- The newest generation product of its re-engineered and miniaturized portable IMS chemical and explosive "sniffer" device;

-- A working model of the AirCHX downdraft inspection workstation based on DualDraw's patented downdraft technology and enhanced with Isonics IMS sniffer technology. AirCHX, produced under a strategic partnership with DualDraw LLC, is designed to provide protection for mailroom workers and others who may be exposed to toxic or explosive threats.

-- Demonstrations of the face recognition and "object left behind" features of its intelligent video security surveillance technology being offered with strategic partner, Intelligent Security Systems, Inc., (ISS) a leading global video security technology developer. The Isonics-ISS intelligent video solutions offer such other security features as iris recognition, object tracking, body tracking and behavior recognition, and auto license plate recognition.

"Isonics has built a formidable pipeline of products andtechnologies that are all designed to provide significant functionaland competitive advantages in a number of homeland security segmentswhere the identified needs are not adequately met by currentsolutions," said James E. Alexander, CEO of Isonics. "Buyers ingovernment and private industry have already demonstrated stronginterest in our products and services. The ISC West trade show willprovide us an excellent opportunity to continue broadening ourcontacts with prospective customers."

The ISC West conference is one of the nation's largest and mostattended security industry events. It brings together leading buyersand sellers of new products, technologies and solutions, providesspecial sessions on industry trends and technologies, and serves as aforum to exchange ideas and conduct business. It will take place April5-7, 2006, at the Sands Expo and Convention Center in Las Vegas, Nev.Former U.S. Department of Homeland Security Secretary Tom Ridge willbe the keynote speaker. For more information, please visithttp://www.iscwest.com.

About Isonics Corporation

Isonics Corporation has three business divisions: (1) HomelandSecurity and Defense, (2) Semiconductor, and (3) Life Sciences.Isonics is a world leader in isotopically engineered materials andthrough its semiconductor division produces isotopically puresilicon-28 chemicals, silicon-on-insulator wafers, wafer reclaimservices and test wafers, including 300mm, for the semiconductorindustry. Isonics' Life Sciences division markets and sells isotopesto the health care industry for the imaging and treatment of cancer.Stable isotopes can be thought of as ultra pure materials. This highdegree of purification provides enhanced properties as compared tonatural materials. Our efforts in the Homeland Security segment arenascent (notwithstanding our operations at Protection Plus SecurityCorporation) at the present time as we proceed to develop further ourIMS and neutron-based detection technologies. Additional informationmay be obtained at http://www.trilogy-capital.com/tcp/isonics, or atthe Company's Website at www.isonics.com.

Cautionary Statement

Except for historical information contained herein, this documentcontains forward-looking statements within the meaning of the PrivateSecurities Litigation Reform Act of 1995. These statements involveestimates, assumptions, known and unknown risks and uncertainties thatmay cause the Company's actual results or outcomes to be materiallydifferent from those anticipated and discussed herein. Further, theCompany operates in industries where securities values may be volatileand may be influenced by regulatory and other factors beyond theCompany's control. Other important factors that the Company believesmight cause such differences are discussed in the risk factorsdetailed in the Company's 10-KSB for the year ended April 30, 2005 andreports subsequently filed with the Securities and ExchangeCommission, which include the Company's historical cash flowdifficulties, dependence on significant customers, and rapiddevelopment of technology, among other risks. In assessingforward-looking statements contained herein, readers are urged tocarefully read all cautionary statements contained in these filingswith the Securities and Exchange Commission.