EANS-PVR: SYGNIS Pharma AG / Release according to article 26, section 1 WpHG (Securities Trading Act) with the aim of Europe-wide distribution

=------------------------------------------------------------------------------- Notification of voting rights transmitted by euro adhoc. The issuer is responsible for the content of this announcement. =-------------------------------------------------------------------------------

Announcement according to Article 21, Section 1 of the WpHG (share)

Person/company obliged to make the notification: =---------------------------------- Name: Margarita Salas Falgueras State: Spain

1. Mrs. Margarita Salas Falgueras, Spain, has notified us pursuant to section 21 (1) WpHG on December 20, 2012, that her percentage of voting rights in SYGNIS Pharma AG rose above the thresholds of 3% and 5% on December 4, 2012 and amounts to 6.21 % (580,186 voting rights versus to a total amount of 9,349,724 voting rights) as per this date

end of announcement euro adhoc =-------------------------------------------------------------------------------

(END) Dow Jones Newswires

   December 20, 2012 11:26 ET (16:26 GMT)- - 11 26 AM EST 12-20-12